The workshop will showcase recent research in the field of Computational Biology. There has been significant development in genomic sequencing techniques as well as imaging technologies that not only generate huge amounts of data but provide unprecedented levels of resolution, that of a single cell and even subcellular resolution. This availability of high dimensional data, at multiple spatial and temporal resolutions and capturing several perspectives of biological phenomena has made machine learning methods increasingly relevant for computational analysis of the data. Conversely, biological data has also exposed unique challenges and problems that call for the development of new machine learning methods. This workshop aims at bringing in researchers working at the intersection of Machine Learning and Biology to present recent advances and open questions in computational biology to the ICML community.