Unsupervised domain adaptation (UDA) aims to leverage the knowledge learned from a labeled source dataset to solve similar tasks in a new unlabeled domain. Prior UDA methods typically require to access the source data when learning to adapt the model, making them risky and inefficient for decentralized private data. This work tackles a novel setting where only a trained source model is available and investigates how we can effectively utilize such a model without source data to solve UDA problems. We propose a simple yet generic representation learning framework, named Source HypOthesis Transfer (SHOT). SHOT freezes the classifier module (hypothesis) of the source model and learns the target-specific feature extraction module by exploiting both information maximization and self-supervised pseudo-labeling to implicitly align representations from the target domains to the source hypothesis. To verify its versatility, we evaluate SHOT in a variety of adaptation cases including closed-set, partial-set, and open-set domain adaptation. Experiments indicate that SHOT yields state-of-the-art results among multiple domain adaptation benchmarks.