MultImp: Multiomics Generative Models for Data Imputation

In biomedical applications, patients are often profiled with multiple technologies or assays to produce a multiomics or multiview biological dataset. A challenge in collecting these datasets is that there are often entire views or individual features missing, which can significantly limit the accuracy of downstream tasks, such as, predicting a patient phenotype. Here, we propose a multiview based deep generative adversarial data imputation model (MultImp). MultImp improves imputation quality and disease subtype classification accuracy in comparison to several baseline methods across two multiomics datasets.